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日本一项基于人群的研究中的角膜厚度及相关因素:多治见研究

Corneal thickness and relating factors in a population-based study in Japan: the Tajimi study.

作者信息

Tomidokoro Atsuo, Araie Makoto, Iwase Aiko

机构信息

Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.

出版信息

Am J Ophthalmol. 2007 Jul;144(1):152-4. doi: 10.1016/j.ajo.2007.02.031.

DOI:10.1016/j.ajo.2007.02.031
PMID:17601447
Abstract

PURPOSE

To evaluate central corneal thickness (CCT) in a Japanese population and to describe the relationship between CCT and other factors.

DESIGN

Population-based cross-sectional study.

METHODS

Reliable CCT measurements were obtained using specular-type pachymetry from 2,868 persons 40 years or older selected randomly from the population of Tajimi City.

RESULTS

The CCT averaged 0.521 +/- 0.032 mm (mean +/- standard deviation). The CCT was thicker in men than in women (P < .001) and was correlated with age (right eyes only), height, weight, diastolic blood pressure, systolic blood pressure (left eyes only), intraocular pressure (IOP), and corneal curvature (P < .05, the Pearson correlation analyses). Multiple regression analysis showed that only gender, IOP, and corneal curvature were significantly (P < .011) associated with CCT.

CONCLUSIONS

The mean CCT obtained using an optical method in a Japanese population was 0.521 mm. The CCT was associated significantly with gender, IOP, and corneal curvature but not with age in multiple regression analyses.

摘要

目的

评估日本人群的中央角膜厚度(CCT),并描述CCT与其他因素之间的关系。

设计

基于人群的横断面研究。

方法

使用镜面式测厚法对从多治见市人群中随机选取的2868名40岁及以上人群进行可靠的CCT测量。

结果

CCT平均为0.521±0.032毫米(平均值±标准差)。男性的CCT比女性厚(P<.001),并且与年龄(仅右眼)、身高、体重、舒张压、收缩压(仅左眼)、眼压(IOP)和角膜曲率相关(P<.05,Pearson相关分析)。多元回归分析表明,仅性别、IOP和角膜曲率与CCT显著相关(P<.011)。

结论

在日本人群中使用光学方法测得的平均CCT为0.521毫米。在多元回归分析中,CCT与性别、IOP和角膜曲率显著相关,但与年龄无关。

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