Kavantzas Nikolaos, Paraskevakou Helen, Tseleni-Balafouta Sofia, Aroni Kyriaki, Athanassiades Pauline, Agrogiannis George, Patsouris Efstratios
Department of Pathology, School of Medicine, National and Kapodistrian University of Athens, Athens, GR-157 73, Greece.
Pathol Oncol Res. 2007;13(2):145-8. doi: 10.1007/BF02893490. Epub 2007 Jul 3.
Angiogenesis seems to contribute to tumor growth and the development of metastases. There may be an association between the vascular density of individual tumors and their prognosis. In the present survey we studied 53 cases of renal cell carcinoma investigating possible relationship between histologic grade and microvessel density (MVD) measured by an image analysis system. According to our results MVD was significantly associated with the histologic grade, higher grades being accompanied with a higher MVD. Further studies are needed to investigate a possible connection of MVD with the prognostic role of grade in RCCs.
血管生成似乎有助于肿瘤生长和转移的发生。单个肿瘤的血管密度与其预后之间可能存在关联。在本次研究中，我们对53例肾细胞癌病例进行了研究，通过图像分析系统测量组织学分级与微血管密度（MVD）之间的可能关系。根据我们的结果，MVD与组织学分级显著相关，分级越高，MVD越高。需要进一步研究来探讨MVD与肾细胞癌分级预后作用之间的可能联系。
