Pohanka Miroslav, Jun Daniel, Kuca Kamil
Centre of Biological Defense, Techonín, Central Military Institute of Health, Techonin, Czech Republic.
Drug Chem Toxicol. 2007;30(3):253-61. doi: 10.1080/01480540701375232.
Toxic fungal metabolites - mycotoxins - cause poisonings after consumption of contaminated food commodities. The most probable intoxications are connected with eating poorly stored food or inhaling of moldy dust. One of the effective ways to protect people against mycotoxins is timely detection. Several methods such as affinity chromatography and enzyme-linked immunosorbent assay are commercially available for this purpose. Nevertheless, fast, sensitive, simple, portable, and low-cost devices are difficult to find. Application of biosensors appears to be a possible method to meet this need for mycotoxins assay.
有毒真菌代谢产物——霉菌毒素——在食用受污染的食品后会导致中毒。最有可能的中毒情况与食用储存不当的食物或吸入发霉的灰尘有关。保护人们免受霉菌毒素侵害的有效方法之一是及时检测。为此,有几种方法如亲和色谱法和酶联免疫吸附测定法在商业上是可用的。然而,很难找到快速、灵敏、简单、便携且低成本的设备。生物传感器的应用似乎是满足霉菌毒素检测这一需求的一种可能方法。