β-半乳糖苷酶合成的转录及转录后调控
Transcriptional and post-transcriptional control of beta-galactosidase synthesis.
作者信息
Ennis H L, Kievitt K D
出版信息
J Bacteriol. 1976 Mar;125(3):1220-2. doi: 10.1128/jb.125.3.1220-1222.1976.
Abstract
lac messenger ribonucleic acid synthesis is dissociated from its translation in certain lac operon mutants. More beta-galactosidase messenger ribonucleic acid (as determined by hybridization) is made in fully induced lacOc mutants and in trp-lac fusions than is eventually translated into enzyme. Consequently, beta-galactosidase synthesis may be post-transcriptionally controlled under these conditions.
摘要
在某些乳糖操纵子突变体中，乳糖信使核糖核酸的合成与其翻译过程相分离。在完全诱导的乳糖操纵子组成型突变体（lacOc）和色氨酸-乳糖融合体中，所产生的β-半乳糖苷酶信使核糖核酸（通过杂交测定）比最终被翻译成酶的量更多。因此，在这些条件下，β-半乳糖苷酶的合成可能受到转录后调控。
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