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与灵芝蘑菇粉相关的致死性暴发性肝炎。

Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder.

作者信息

Wanmuang Harirak, Leopairut Juvady, Kositchaiwat Chomsri, Wananukul Winai, Bunyaratvej Sukhum

机构信息

Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 2007 Jan;90(1):179-81.

Abstract

Hepatotoxic effect related to Ganoderma lucidum (Lingzhi) mushroom powder was first described in a patient from Hong Kong in 2004. In 2005, the authors experienced a case of fatal fulminant hepatitis associated with such a preparation. Both patients had taken other therapeutic agents and traditionally boiled Lingzhi without any toxic effect. After switching to taking Lingzhi in powder form for 1-2 months, the hepatotoxic episode occurred in both patients. The toxic role of Lingzhi powder needs close monitoring in the future, especially in combination with other drugs.

摘要

与灵芝(灵芝)蘑菇粉相关的肝毒性作用于2004年在一名来自香港的患者中首次被描述。2005年,作者遇到了一例与此类制剂相关的致命暴发性肝炎病例。两名患者都服用了其他治疗药物,并且传统上煮灵芝时没有任何毒性作用。在改用粉末形式的灵芝服用1-2个月后,两名患者均发生了肝毒性事件。未来需要密切监测灵芝粉的毒性作用,尤其是与其他药物联合使用时。

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