Wanmuang Harirak, Leopairut Juvady, Kositchaiwat Chomsri, Wananukul Winai, Bunyaratvej Sukhum
Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
J Med Assoc Thai. 2007 Jan;90(1):179-81.
Hepatotoxic effect related to Ganoderma lucidum (Lingzhi) mushroom powder was first described in a patient from Hong Kong in 2004. In 2005, the authors experienced a case of fatal fulminant hepatitis associated with such a preparation. Both patients had taken other therapeutic agents and traditionally boiled Lingzhi without any toxic effect. After switching to taking Lingzhi in powder form for 1-2 months, the hepatotoxic episode occurred in both patients. The toxic role of Lingzhi powder needs close monitoring in the future, especially in combination with other drugs.
与灵芝(灵芝)蘑菇粉相关的肝毒性作用于2004年在一名来自香港的患者中首次被描述。2005年,作者遇到了一例与此类制剂相关的致命暴发性肝炎病例。两名患者都服用了其他治疗药物,并且传统上煮灵芝时没有任何毒性作用。在改用粉末形式的灵芝服用1-2个月后,两名患者均发生了肝毒性事件。未来需要密切监测灵芝粉的毒性作用,尤其是与其他药物联合使用时。