Cör Andrejč Darija, Knez Željko, Knez Marevci Maša
Faculty of Chemistry and Chemical Engineering, Maribor, Slovenia.
Laboratory Faculty of Medicine, Maribor, Slovenia.
Front Pharmacol. 2022 Jul 22;13:934982. doi: 10.3389/fphar.2022.934982. eCollection 2022.
is a very medicinal mushroom that has been utilized in Oriental medicine for many years. It has a wide range of pharmacological and therapeutic properties, and has been used for many years as a health promoter. It contains various biologically active compounds that improve the immune system and have antioxidant, antitumor, anti-inflammatory, antifungal, and antimicrobial properties. Active compounds include triterpenoids and polysaccharides, as well as proteins, lipids, phenolics, sterols, etc. In the following review, we summarize briefly their biological activities, such as antioxidant, anti-bacterial, anti-fungal, antitumor, anti-viral, and anti-inflammatory activity. Although has a number of medicinal effects that have been confirmed by the and studies summarised in this review, there are some limitations. Clinical trials face mainly a lack of pure constituents. Accurate identification of the compounds obtained is also problematic. In addition, most of the included studies were small, and there were concerns about the methodological quality of each study. Studies have shown that Ganoderma has valuable potential for the prevention and treatment of cancer. In any case, cannot be used as first-line therapy for cancer.
是一种非常具有药用价值的蘑菇，在东方医学中已被使用多年。它具有广泛的药理和治疗特性，多年来一直被用作健康促进剂。它含有多种生物活性化合物，可增强免疫系统，并具有抗氧化、抗肿瘤、抗炎、抗真菌和抗菌特性。活性化合物包括三萜类化合物和多糖，以及蛋白质、脂质、酚类、甾醇等。在以下综述中，我们简要总结它们的生物活性，如抗氧化、抗菌、抗真菌、抗肿瘤、抗病毒和抗炎活性。尽管本综述总结的研究已经证实具有多种药用效果，但仍存在一些局限性。临床试验主要面临缺乏纯成分的问题。对所获得化合物的准确鉴定也存在问题。此外，大多数纳入研究规模较小，且对每项研究的方法学质量存在担忧。研究表明，灵芝在癌症预防和治疗方面具有宝贵的潜力。无论如何，灵芝不能用作癌症的一线治疗药物。
