Sripa Banchob, Kaewkes Sasithorn, Sithithaworn Paiboon, Mairiang Eimorn, Laha Thewarach, Smout Michael, Pairojkul Chawalit, Bhudhisawasdi Vajaraphongsa, Tesana Smarn, Thinkamrop Bandit, Bethony Jeffrey M, Loukas Alex, Brindley Paul J
Department of Pathology, Khon Kaen University, Khon Kaen, Thailand.
PLoS Med. 2007 Jul;4(7):e201. doi: 10.1371/journal.pmed.0040201.
The authors discuss the molecular pathogenesis of opisthorchiasis and associated cholangiocarcinogenesis, particularly nitrative and oxidative DNA damage and the clinical manifestations of cholangiocarcinoma.
作者们讨论了华支睾吸虫病的分子发病机制及相关胆管癌发生机制,尤其是硝化和氧化DNA损伤以及胆管癌的临床表现。