Norris Vic, Hunding Axel, Kepes Francois, Lancet Doron, Minsky Abraham, Raine Derek, Root-Bernstein Robert, Sriram K
AMMIS Laboratory, UMR CNRS 6522, University of Rouen, Mont Saint Aignan, 76821, France.
Orig Life Evol Biosph. 2007 Oct;37(4-5):429-32. doi: 10.1007/s11084-007-9088-z. Epub 2007 Jul 10.
Five common assumptions about the first cells are challenged by the pre-biotic ecology model and are replaced by the following propositions: firstly, early cells were more complex, more varied and had a greater diversity of constituents than modern cells; secondly, the complexity of a cell is not related to the number of genes it contains, indeed, modern bacteria are as complex as eukaryotes; thirdly, the unit of early life was an 'ecosystem' rather than a 'cell'; fourthly, the early cell needed no genes at all; fifthly, early life depended on non-covalent associations and on catalysts that were not confined to specific reactions. We present here the outlines of a theory that connects findings about modern bacteria with speculations about their origins.
关于第一批细胞的五个常见假设受到了前生物生态模型的挑战,并被以下观点所取代:首先,早期细胞比现代细胞更复杂、更多样,其组成成分也更多样化;其次,细胞的复杂性与其所含基因的数量无关,实际上,现代细菌与真核生物一样复杂;第三,早期生命的单位是“生态系统”而非“细胞”;第四,早期细胞根本不需要基因;第五,早期生命依赖于非共价结合以及不限于特定反应的催化剂。我们在此提出一种理论的梗概,该理论将关于现代细菌的发现与对其起源的推测联系起来。