唐古特瑞香根提取物及化合物的抗肿瘤活性
Antitumor activities of extracts and compounds from the roots of Daphne tangutica Maxim.
作者信息
Zhang Wei, Zhang Wei-Dong, Zhang Chuan, Liu Run-Hui, Li Ting-Zhao, Fu Peng, Shan Lei
机构信息
School of Pharmacy, Second Military Medical University, Shanghai 200433, P. R. China.
出版信息
Phytother Res. 2007 Nov;21(11):1113-5. doi: 10.1002/ptr.2227.
The antitumor activities of the crude extracts of Daphne tangutica Maxim. (Thymelaeaceae) and some compounds were investigated in vivo for the first time. The eight tested samples exhibited inhibition in mice transplanted with sarcoma S180. Of the eight samples, two samples DTE-2 (mixture of daphnodorin E and daphnodorin F) and DTE-3 (syringin) were noted to have the most marked antitumor activity.
首次在体内研究了唐古特瑞香（瑞香科）粗提物及一些化合物的抗肿瘤活性。对八个受试样品进行了肉瘤S180移植小鼠体内抑制试验。在这八个样品中，两个样品DTE - 2（瑞香毒素E和瑞香毒素F的混合物）和DTE - 3（紫丁香苷）具有最显著的抗肿瘤活性。
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