Kelly Justin, Leader Mary, Broe Patrick
Department of General Surgery, Beaumont Hospital, Dublin 9, Ireland.
J Med Case Rep. 2007 Jul 14;1:50. doi: 10.1186/1752-1947-1-50.
Primary malignant melanoma of the oesophagus is a rare neoplasm comprising less than 0.2% of all primary oesophageal neoplasms. There are fewer than 250 reported cases in worldwide literature. Several reports suggest that it has a mean survival rate of 2.2% at 5 years and a median survival rate of 10 months. A 48 year old male presented to our surgical service complaining of a three month history of progressively worsening dysphagia with associated regurgitation and unintentional weight loss of 14 kg. There was no prior history of cutaneous or ocular melanoma. He was treated with a combination of subtotal oesophageal resection and immunomodulatory therapy. We present herein a case of primary malignant melanoma of the oesophagus including the associated clinical, pathological and radiological findings.
原发性食管恶性黑色素瘤是一种罕见的肿瘤，占所有原发性食管肿瘤的比例不到0.2%。全球文献报道的病例少于250例。几份报告表明，其5年平均生存率为2.2%，中位生存率为10个月。一名48岁男性因进行性吞咽困难伴反流3个月、体重意外减轻14kg就诊于我们的外科。既往无皮肤或眼部黑色素瘤病史。他接受了食管次全切除术和免疫调节治疗。我们在此报告一例原发性食管恶性黑色素瘤病例，包括相关的临床、病理和影像学表现。
