Kang Min-Jung, Yi Sun Young
Department of Internal Medicine, School of Medicine, 158-056 Ewha Womans University, 911-1 Mokdong Yangcheon-Ku, Seoul, South Korea.
Gastroenterol Res Pract. 2009;2009:285753. doi: 10.1155/2009/285753. Epub 2009 Jul 27.
The primary malignant melanoma of the esophagus (PMME) is a rare malignant disease, accounting for only 0.1-0.2% of all esophageal neoplasms, and the majority of the patients are diagnosed at advanced stages with poor prognosis. We present here a case of 56-year-old woman with epigastric pain and her endoscopic finding revealed several flat and black pigmented mucosal lesions within the distal portion of the esophagus which looked like flat nevus. The histopathology and immunohistochemical profile of the tissue specimens were diagnostic of malignant melanoma.
原发性食管恶性黑色素瘤(PMME)是一种罕见的恶性疾病,仅占所有食管肿瘤的0.1-0.2%,大多数患者在晚期被诊断出来,预后较差。我们在此报告一例56岁女性,有上腹部疼痛,其内镜检查发现食管远端有几个扁平的黑色色素沉着黏膜病变,看起来像扁平痣。组织标本的组织病理学和免疫组化特征诊断为恶性黑色素瘤。