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[食物过敏和不耐受反应]

[Food allergies and intolerance reactions].

作者信息

Thiel C

机构信息

Deutsche Klinik für Diagnostik, Fachbereich Allergologie, Wiesbaden.

出版信息

Z Ernahrungswiss. 1991 Sep;30(3):158-73. doi: 10.1007/BF01610339.

Abstract

Adverse reactions to food and food additives are defined by its different pathomechanisms. Clinically most important are allergic (immunologic) reactions (types I and III), which occur in 7-10% of the general population, and nonimmunologic (pseudoallergic) reactions (PAR), which occur in 1-2%, besides nonallergic reactions by vasoactive amines. Clinical features are equal. Sources of antigens for allergic reactions are proteins of cow's milk, fish, hen's egg, meat, and all kinds of cereals, fruits, vegetables, and spices, while pseudoallergic reactions are induced by chemicals (preservatives, colorants, antioxidants). The diagnostic procedures of allergic reactions include the proof of sensitization by case history, skin test, specific IgE (and IgG) in-vitro, elimination diet and provocation test; pseudoallergic reactions with no underlying sensitization are diagnosed only by elimination and provocation procedures.

摘要

对食物和食物添加剂的不良反应是由其不同的发病机制所定义的。临床上最重要的是过敏(免疫性)反应(I型和III型),在普通人群中发生率为7-10%,以及非免疫性(假过敏)反应(PAR),发生率为1-2%,此外还有血管活性胺引起的非过敏反应。临床特征相同。过敏反应的抗原来源是牛奶、鱼类、鸡蛋、肉类以及各种谷物、水果、蔬菜和香料中的蛋白质,而假过敏反应则由化学物质(防腐剂、色素、抗氧化剂)诱发。过敏反应的诊断程序包括通过病史、皮肤试验、体外特异性IgE(和IgG)、排除饮食和激发试验来证明致敏;无潜在致敏的假过敏反应仅通过排除和激发程序来诊断。

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