Turner Thomas L, Hahn Matthew W
Center for Population Biology, University of California, Davis, USA.
Mol Biol Evol. 2007 Sep;24(9):2132-8. doi: 10.1093/molbev/msm143. Epub 2007 Jul 17.
Anopheles gambiae, the primary mosquito vector of malaria in sub-Saharan Africa, is divided into 2 sympatric incipient species known as M form and S form. Recent genomic analysis of each form revealed that differentiation between forms is clustered into 3 unlinked regions of the genome. Here, we expand the investigation of these "genomic islands of speciation" to multiple populations, including all of the genes across one of the islands. Differentiation between the M and S forms in 2 of the islands is complete across all individuals in all populations, confirming that the M and S forms are reproductively isolated taxa. Differentiation at the third island (on chromosome 2R) is limited to Cameroon populations. There is reduced variation in the M form in Cameroon at this location and increased divergence to the outgroup Anopheles arabiensis, supporting an association of adaptation with reproductive isolation.
冈比亚按蚊是撒哈拉以南非洲地区疟疾的主要传播媒介，它分为两种同域分布的初始物种，即M型和S型。最近对每种类型的基因组分析表明，不同类型之间的分化集中在基因组的3个不连锁区域。在这里，我们将对这些“物种形成的基因组岛”的研究扩展到多个种群，包括其中一个岛上的所有基因。在所有种群的所有个体中，两个岛上的M型和S型之间的分化是完全的，这证实了M型和S型是生殖隔离的分类群。第三个岛（位于2R染色体上）的分化仅限于喀麦隆种群。在这个位置，喀麦隆的M型变异减少，与外群阿拉伯按蚊的差异增加，这支持了适应性与生殖隔离之间的关联。
