Civelekoglu-Scholey Gul, Scholey Jonathan M
Department of Molecular and Cell Biology, University of California at Davis, Davis, CA 95616, USA.
Curr Biol. 2007 Jul 17;17(14):R544-7. doi: 10.1016/j.cub.2007.05.030.
A kinesin-5-dependent 'sliding filament' mechanism is commonly used to actively push apart the poles during mitotic spindle assembly and elongation, but a recent study now shows that, in C. elegans, kinesin-5 is deployed as a brake to slow down spindle-pole separation.
驱动蛋白-5依赖的“滑动丝”机制通常用于在有丝分裂纺锤体组装和延长过程中主动推开两极，但最近一项研究表明，在秀丽隐杆线虫中，驱动蛋白-5被用作一种制动器来减缓纺锤体极分离。
