沙拐枣的甲醇、水和正己烷提取物中的抗真菌活性。

Antifungal activity in the methanolic, aqueous and hexane extracts of Calligonum polygonoides.

机构信息

1 College of Agriculture, University of Sargodha, Sargodha, Pakistan.

2 Department of Eastern Medicine, Directorate of Medical Sciences, Government College University Faisalabad, Faisalabad, Pakistan.

出版信息

Int J Immunopathol Pharmacol. 2019 Jan-Dec;33:2058738418821275. doi: 10.1177/2058738418821275.

DOI:10.1177/2058738418821275

PMID:30791750

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6327324/

Abstract

Calligonum polygonoides is locally called as Phog which belongs to the Polygonaceae family. It is traditionally used as an antifungal. The methanolic extract, hexane extract, ethyl acetate extract and aqueous extract were screened against Candida albicans and Aspergillus niger in seven concentrations, that is, 1.8, 2.9, 6.5, 12.6, 25, 50 and 75 µg/mL/disc. Calligonum polygonoides showed significant activity against Candida albicans as the observed minimum inhibitory concentration (MIC) is 6.5 µg/mL for methanolic extract, 9.8 µg/mL for ethyl acetate extract, whereas aqueous and hexane extracts showed no activity. Calligonum polygonoides did not show any significant activity against Aspergillus niger.

摘要

沙拐枣在当地被称为 Phog，属于蓼科。它被传统用作抗真菌药物。甲醇提取物、正己烷提取物、乙酸乙酯提取物和水提取物在七种浓度下（即 1.8、2.9、6.5、12.6、25、50 和 75μg/mL/片）对白色念珠菌和黑曲霉进行了筛选。沙拐枣对白色念珠菌表现出显著的活性，因为其甲醇提取物的最小抑菌浓度（MIC）为 6.5μg/mL，乙酸乙酯提取物为 9.8μg/mL，而水提取物和正己烷提取物则没有活性。沙拐枣对黑曲霉没有表现出任何显著的活性。