Duracinsky Martin, Mosnier Isabelle, Bouccara Didier, Sterkers Olivier, Chassany Olivier
Internal Medicine Department, Hôpital Bicêtre, AP-HP, Kremlin Bicêtre, France.
Value Health. 2007 Jul-Aug;10(4):273-84. doi: 10.1111/j.1524-4733.2007.00182.x.
Vertigo and dizziness, which are major symptoms of diseases affecting the vestibular system, drastically impair patients' health-related quality of life (QoL). Patient's perspectives are thus essential to symptom assessment. We sought to make a critical review of published questionnaires measuring vertigo or dizziness, and/or their impact on QoL.
Twenty-nine articles reporting the validation or use in clinical trials of vertigo- or dizziness-specific questionnaires were identified over the 1991-2004 period, and reviewed using a methodological and a Patient-Reported Outcomes specific checklist. Questionnaires were classified into three categories according to content: QoL (or handicap), mixed (assessing both symptoms and QoL), and symptom questionnaires.
Four QoL, three mixed questionnaires, two symptoms, and one Meniere's disease-specific questionnaire were identified. QoL questionnaire validation was usually not complete. The structural validity of the Dizziness Handicap Inventory is not established, although this questionnaire is considered to be the reference questionnaire in the QoL domain. Moreover, QoL questionnaires were not very specific to vertigo or dizziness. Similarly, the Vertigo Handicap Questionnaire appeared to have the most pertinent content, but its validation remains to be completed. Mixed questionnaires have the same imperfections. The Vertigo, Dizziness, Imbalance (VDI) Questionnaire had the best validation score from the checklist, but its responsiveness appears to be weak. Regarding symptom questionnaires, the European Evaluation of Vertigo questionnaire evaluated the five major symptoms of vestibular syndrome satisfactorily.
The present literature review failed to find any relevant and validated questionnaire assessing the impact of vertigo or dizziness on QoL.
眩晕和头晕是影响前庭系统疾病的主要症状,严重损害患者的健康相关生活质量(QoL)。因此,患者的观点对于症状评估至关重要。我们试图对已发表的测量眩晕或头晕及/或其对生活质量影响的问卷进行批判性综述。
在1991 - 2004年期间,确定了29篇报告眩晕或头晕特异性问卷在临床试验中的验证或使用情况的文章,并使用方法学和患者报告结局特定清单进行综述。问卷根据内容分为三类:生活质量(或残疾)问卷、混合问卷(评估症状和生活质量)和症状问卷。
确定了4种生活质量问卷、3种混合问卷、2种症状问卷和1种梅尼埃病特异性问卷。生活质量问卷的验证通常不完整。尽管眩晕残疾量表被认为是生活质量领域的参考问卷,但其结构效度尚未确立。此外,生活质量问卷对眩晕或头晕的特异性不强。同样,眩晕残疾问卷似乎具有最相关的内容,但其验证仍有待完成。混合问卷也有同样的缺陷。眩晕、头晕、失衡(VDI)问卷在清单中的验证得分最高,但其反应度似乎较弱。关于症状问卷,欧洲眩晕评估问卷对前庭综合征的五大主要症状评估令人满意。
本次文献综述未能找到任何评估眩晕或头晕对生活质量影响的相关且经过验证的问卷。