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氟喹诺酮相关性肌腱病:一例报告。

Fluoroquinolone-associated tendinopathy: a case report.

作者信息

Ng Wan-Fai, Naughton Michael

机构信息

Department of Rheumatology, Ealing Hospital NHS Trust, Ealing, Southall, UB1 3UJ UK.

出版信息

J Med Case Rep. 2007 Jul 23;1:55. doi: 10.1186/1752-1947-1-55.

Abstract

Fluoroquinolone-associated tendinopathy is well described. This adverse effect however does not appear to be widely known among medical practitioners. We hereby described a case of ciprofloxacin-associated tendinopathy for which the adverse drug reaction was not suspected initially and the patient was inappropriately reassured and incorrectly advised to complete the antibiotic course. Given the frequent use of fluoroquinolones in clinical practice and the potential for severe disability from tendon rupture, we consider it important to remind your readers of this uncommon but potentially devastating adverse drug reaction.

摘要

氟喹诺酮类药物相关的肌腱病已有充分描述。然而,这种不良反应在医学从业者中似乎并未广为人知。我们在此描述一例环丙沙星相关的肌腱病病例,该病例最初未怀疑有药物不良反应,患者得到了不恰当的安慰,并被错误地建议完成抗生素疗程。鉴于氟喹诺酮类药物在临床实践中经常使用,且肌腱断裂可能导致严重残疾,我们认为提醒读者注意这种罕见但可能具有毁灭性的药物不良反应很重要。

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本文引用的文献

1
Fluoroquinolone-associated tendinopathy: a critical review of the literature.氟喹诺酮相关性肌腱病:文献综述
Clin Infect Dis. 2003 Jun 1;36(11):1404-10. doi: 10.1086/375078. Epub 2003 May 20.
5
Achilles tendinitis associated with fluoroquinolones.与氟喹诺酮类药物相关的跟腱炎。
Br J Clin Pharmacol. 1999 Sep;48(3):433-7. doi: 10.1046/j.1365-2125.1999.00016.x.

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