Krahe T, Schindler R, Neubauer S, Hillenbrand H, Lackner K, Boesiger P, McKinnon G, Landwehr P, Ertl G
Institut für Röntgendiagnostik, Universität Würzburg.
Rofo. 1991 Dec;155(6):506-12. doi: 10.1055/s-2008-1033307.
31P-magnetic resonance (MR) spectra of the heart can be obtained from well-defined myocardial regions by combined MR imaging and variable selected volumes for spectroscopy. 31P-spectra of 33 volunteers and of 43 patients with dilated and hypertrophic cardiomyopathy and with coronary artery disease were quantified using a curve-fitting routine. To optimize our technique, we recorded unsaturated and partially saturated spectra in several volunteers. Relative peak areas and signal-to-noise ratios showed significant changes with varying pulse repetition times. Saturation factors were applied to correct spectra from volunteers and patients for the effects of partial saturation. Under resting conditions, peak areas of volunteers and patients from the various groups were statistically indistinct.
通过磁共振成像（MR）与用于光谱分析的可变选定容积相结合，可从明确界定的心肌区域获取心脏的31P磁共振（MR）光谱。使用曲线拟合程序对33名志愿者以及43名患有扩张型和肥厚型心肌病及冠状动脉疾病的患者的31P光谱进行了定量分析。为优化我们的技术，我们在数名志愿者身上记录了不饱和及部分饱和光谱。相对峰面积和信噪比随脉冲重复时间的变化呈现出显著改变。应用饱和因子对志愿者和患者的光谱进行校正，以消除部分饱和的影响。在静息状态下，各分组中志愿者和患者的峰面积在统计学上无明显差异。
