Truhan A P
Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, Boston 02114.
Clin Pediatr (Phila). 1991 Dec;30(12):676-81. doi: 10.1177/000992289103001205.
There is compelling evidence that childhood is a particularly vulnerable time for the photocarcinogenic effects of sun exposure on the skin. Studies indicate that excessive sun exposure during the first 10-20 years of life greatly increases the risk of skin cancer. Nonmelanoma skin cancer (basal cell and squamous cell carcinoma) has been associated with cumulative sun exposure, whereas melanoma has been associated with short, intense sun exposure or blistering sunburn. Under normal circumstances, children receive three times the annual sun exposure of adults; most of one's lifetime sun exposure occurs in childhood. Depletion of the earth's protective ozone layer adds to the photodamage problem. It is clear that sun protection is most vital in the early years. Those with fair skin are at highest risk. Photoprotective measures including sunscreen, clothing, and sun avoidance in childhood may significantly reduce the occurrence of melanoma and other skin cancer in later life. Regular use of sunscreen with a sun protection factor of 15 during the first 18 years of life could reduce the lifetime incidence of nonmelanoma skin cancer by 78%. Pediatricians can play a major role in educating parents and children.
有令人信服的证据表明,童年时期是阳光照射对皮肤产生光致癌作用的特别脆弱时期。研究表明,在生命的最初10至20年过度暴露于阳光下会大大增加患皮肤癌的风险。非黑色素瘤皮肤癌(基底细胞癌和鳞状细胞癌)与累积的阳光照射有关,而黑色素瘤则与短期强烈的阳光照射或晒伤起泡有关。在正常情况下,儿童每年接受的阳光照射量是成年人的三倍;一个人一生中大部分的阳光照射都发生在童年时期。地球保护性臭氧层的消耗加剧了光损伤问题。显然,早期的防晒最为重要。皮肤白皙的人风险最高。童年时期包括使用防晒霜、穿着衣物和避免阳光照射在内的光保护措施可能会显著降低晚年患黑色素瘤和其他皮肤癌的几率。在生命的前18年定期使用防晒系数为15的防晒霜可使非黑色素瘤皮肤癌的终生发病率降低78%。儿科医生在教育家长和孩子方面可发挥重要作用。