Cutting Keith, White Richard, Edmonds Mike
Faculty of Society & Health, Buckinghamshire Chilterns University College, Chalfont St. Giles, HP8 4AD, UK.
Int Wound J. 2007 Jun;4(2):177-84. doi: 10.1111/j.1742-481X.2007.00338.x.
With the increasing use of silver as a topical application in wound care, concerns focussing on its role are bound to arise. These concerns, which centre on issues such as resistance and toxicity, clinical efficacy and cost-effectiveness, need to be addressed and openly discussed so that they are viewed from a rational perspective. While clinical efficacy and safety, along with cost-benefit, are of obvious interest, the origin of some of these concerns is a matter of debate. The silver-containing dressing segment of the medical device market is of huge commercial importance, and, consequently, marketing and promotional issues occasionally obscure the evidence that clinicians need to have in order that they may provide appropriate treatment for their patients. The impact of silver application on the wound bioburden needs to be examined carefully to heighten our awareness of any deleterious effects on the healing process, without inducing any unfounded anxieties.
随着银在伤口护理局部应用中的使用日益增加，必然会引发对其作用的关注。这些关注集中在诸如耐药性和毒性、临床疗效和成本效益等问题上，需要加以解决并进行公开讨论，以便从合理的角度看待它们。虽然临床疗效和安全性以及成本效益显然备受关注，但其中一些关注的根源存在争议。医疗器械市场中含银敷料领域具有巨大的商业重要性，因此，营销和推广问题有时会掩盖临床医生为患者提供适当治疗所需的证据。需要仔细研究银的应用对伤口生物负荷的影响，以提高我们对愈合过程中任何有害影响的认识，同时避免引发无端的焦虑。
