Sirmatel O, Sert C, Sirmatel F, Selek S, Yokus B
Department of Radiodiagnostics, Medicine Faculty of Harran University, Yenişehir Campus, 63100 Sanliurfa, Türkey.
Gen Physiol Biophys. 2007 Jun;26(2):86-90.
The aim of this study was to investigate the effects of a high-strength magnetic field produced by a magnetic resonance imaging (MRI) apparatus on oxidative stress. The effects of a 1.5 T static magnetic field on the total antioxidant capacity (TAC), total oxidant status (TOS) and oxidative stress index (OSI) in male subjects were investigated. In this study, 33 male volunteers were exposed to a 1.5 T static magnetic field for a short time and the TAC, TOS and OSI of each subject were determined. Magnetic field exposure was provided using a magnetic resonance apparatus; radiofrequency was not applied. Blood samples were taken from subjects and TAC, TOS and OSI values were measured using the methods of Erel. TAC showed a significant increase in post-exposures compared to pre-exposures to the magnetic field (p < 0.05). OSI and TOS showed a significant decrease in post-exposures compared to pre-exposures to a 1.5 T magnetic field (for each of two, p < 0.01). The 1.5 T static magnetic field used in the MRI apparatus did not yield a negative effect; on the contrary, it produced the positive effect of decreasing oxidative stress in men following short-term exposure.
本研究的目的是调查磁共振成像(MRI)设备产生的高强度磁场对氧化应激的影响。研究了1.5 T静磁场对男性受试者总抗氧化能力(TAC)、总氧化剂状态(TOS)和氧化应激指数(OSI)的影响。在本研究中,33名男性志愿者短时间暴露于1.5 T静磁场中,并测定了每名受试者的TAC、TOS和OSI。使用磁共振设备提供磁场暴露;未施加射频。从受试者采集血样,并使用Erel的方法测量TAC、TOS和OSI值。与暴露于磁场前相比,暴露后TAC显著增加(p < 0.05)。与暴露于1.5 T磁场前相比,暴露后OSI和TOS显著降低(两者均为p < 0.01)。MRI设备中使用的1.5 T静磁场未产生负面影响;相反,它在短期暴露后对男性产生了降低氧化应激的积极作用。