Ferrari Carlos Kusano Bucalen
Biomedical Research Group, Instituto de Ciências Biológicas e da Saúde (ICBS), Campus Universitário do Araguaia, Universidade Federal de Mato Grosso (UFMT), Av. Gov. Jaime Campos, 6390, Distrito Industrial, Barra do Garças, 78.600-000, MT, Brazil.
Interdiscip Toxicol. 2012 Sep;5(3):117-22. doi: 10.2478/v10102-012-0019-0.
The objective of this article was to review the effects of xenobiotics on total antioxidant capacity (TAC). Measurement of TAC is appropriate for evaluation of the total antioxidant defenses of blood, cells, and different kinds of tissues and organs. TAC is reduced by alcoholism, smoking, and exposure to radiation, herbicides, carbon monoxide, carbon tetrachloride, lead, arsenic, mercury, cadmium, aluminum, and other toxic elements. The test is also an important tool in evaluating environmental and occupational exposure.
本文的目的是综述外源性物质对总抗氧化能力(TAC)的影响。TAC的测定适用于评估血液、细胞以及不同种类组织和器官的总抗氧化防御能力。酗酒、吸烟以及暴露于辐射、除草剂、一氧化碳、四氯化碳、铅、砷、汞、镉、铝和其他有毒元素会使TAC降低。该检测也是评估环境和职业暴露的一项重要工具。