孕期因弓形虫、风疹、巨细胞病毒和沙眼衣原体感染导致的特异性免疫球蛋白M（IgM）的患病率。

Prevalence of specific IGM due to toxoplasma, rubella, CMV and c.trachomatis infections during pregnancy.

作者信息

Yasodhara P, Ramalakshmi B A, Naidu A N, Raman L

机构信息

National Institute of Nutrition, Indian council of Medical Research, Jamai Osmania P.O., Hyderabad, - 500 007, India.

出版信息

Indian J Med Microbiol. 2001 Apr-Jun;19(2):52-6.

PMID:17664809

Abstract

One hundred and seventy five apparently normal asymptomatic pregnant women were studied prospectively and 247 women with different complications of pregnancy were screened at the time of delivery for infections like Chlamydia trachomatis, Toxoplasma, Rubella and cytomegalovirus (CMV). One hundred and forty two women with normal outcome of pregnancy served as controls. Specific IgM due to these agents were determined in the sera using commercial diagnostic kits. Results of the study showed that chlamydial infection was the most prevalent (29.8%) followed by Toxoplasmosis (13.1), Rubella (6.5%) and CMV (5.8%). Adverse outcome was seen among those seropositive for Chlamydia, Toxoplasmosis and Rubella. CMV showed no association with adverse outcome of pregnancy. Since Chlamydia and Toxoplasmosis are amenable to treatment with antibiotics, screening for these infections and appropriate treatment would improve outcome of pregnancy.

摘要

对175名表面上正常且无症状的孕妇进行了前瞻性研究，并在分娩时对247名患有不同妊娠并发症的妇女进行了沙眼衣原体、弓形虫、风疹和巨细胞病毒（CMV）等感染的筛查。142名妊娠结局正常的妇女作为对照。使用商业诊断试剂盒测定血清中这些病原体的特异性IgM。研究结果表明，衣原体感染最为普遍（29.8%），其次是弓形虫病（13.1%）、风疹（6.5%）和CMV（5.8%）。衣原体、弓形虫病和风疹血清阳性者出现了不良结局。CMV与妊娠不良结局无关联。由于衣原体和弓形虫病可用抗生素治疗，对这些感染进行筛查并进行适当治疗将改善妊娠结局。