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凡城孕妇弓形虫、风疹和巨细胞病毒血清阳性率

Seroprevalence of Toxoplasma, Rubella, and Cytomegalovirus among pregnant women in Van.

作者信息

Parlak Mehmet, Çim Numan, Nalça Erdin Begüm, Güven Ayşe, Bayram Yasemin, Yıldızhan Recep

机构信息

Yüzüncü Yıl University Faculty of Medicine, Department of Medical Microbiology, Van, Turkey.

Yüzüncü Yıl University Faculty of Medicine, Department of Obstetrics and Gynecology, Van, Turkey.

出版信息

Turk J Obstet Gynecol. 2015 Jun;12(2):79-82. doi: 10.4274/tjod.35902. Epub 2015 Jun 15.

Abstract

OBJECTIVE

To determine the seroprevalence of anti-Toxoplasma, anti-Rubella, and anti- antibodies among pregnant women receiving prenatal care at Van Training and Research Hospital.

MATERIALS AND METHODS

In developing countries, various infectious agents encountered in the gestational period are important because they influence both maternal and fetal health. Among these, , Rubella and are quite prevalent. In the present study, anti-Toxoplasma, anti-Rubella and anti- antibodies were analyzed in the serum samples obtained from women receiving prenatal care at Van Training and Research Hospital between June 2012 and July 2013, and positive serum samples were retrospectively evaluated. Anti-Toxoplasma, anti-Rubella and anti- antibodies were analyzed using ELISA with Cobas 4000 e411 (Roche, Germany) and Architect i2000SR (Abbott Diagnostics, Germany) analyzers.

RESULTS

Over the course of the study period, the results of a total of 9809 patients were investigated in terms of anti-Toxoplasma, anti-Rubella, and anti-CMV antibodies. Anti-Toxoplasma, anti-Rubella, and anti- IgM and IgG antibody positivity rates were 1.1%, 0.5% and 2.6%, and 37.6%, 86.5% and 100%, respectively.

CONCLUSION

Anti-Toxoplasma IgG antibody positivity rates determined in the present study were lower as compared with the results of the other studies reported from Turkey. However, IgM and IgG antibody positivity rates were be higher as compared with those reported in the literature.

摘要

目的

确定在凡培训与研究医院接受产前检查的孕妇中抗弓形虫、抗风疹和抗[具体病原体]抗体的血清流行率。

材料与方法

在发展中国家,孕期遇到的各种感染因子很重要,因为它们会影响母婴健康。其中,[具体病原体]、风疹和[具体病原体]相当普遍。在本研究中,对2012年6月至2013年7月期间在凡培训与研究医院接受产前检查的妇女的血清样本进行了抗弓形虫、抗风疹和抗[具体病原体]抗体分析,并对阳性血清样本进行了回顾性评估。使用德国罗氏公司的Cobas 4000 e411和德国雅培诊断公司的Architect i2000SR分析仪通过酶联免疫吸附测定法(ELISA)分析抗弓形虫、抗风疹和抗[具体病原体]抗体。

结果

在研究期间,共对9809例患者的抗弓形虫、抗风疹和抗巨细胞病毒(CMV)抗体结果进行了调查。抗弓形虫、抗风疹和抗CMV IgM及IgG抗体阳性率分别为1.1%、0.5%和2.6%,以及37.6%、86.5%和100%。

结论

本研究确定的抗弓形虫IgG抗体阳性率与土耳其其他研究报告的结果相比更低。然而,[具体病原体]IgM和IgG抗体阳性率与文献报道的相比更高。

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