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香港华裔婴儿近视的常染色体隐性遗传

Autosomal recessive inheritance of myopia in Hong Kong Chinese infants.

作者信息

Edwards M, Lewis W H

机构信息

Department of Diagnostic Sciences, Hong Kong Polytechnic.

出版信息

Ophthalmic Physiol Opt. 1991 Jul;11(3):227-31.

PMID:1766686
Abstract

Hong Kong Chinese infants were refracted by retinoscopy at regular intervals between the age of approximately 10 and 40 weeks. Cyclopentolate 1% was used to obtain cycloplegia. The spherical equivalent of the refractive error was calculated for each child and analysis of variance carried out according to the refractive status of the parents. From approximately 20 weeks of age a significant difference was found between the mean spherical equivalent of the refractive error of infants of parents both of whom were myopic and that of infants of parents neither of whom was myopic. At 40 weeks of age a good fit with an autosomal recessive probability model was obtained.

摘要

对香港华裔婴儿在大约10至40周龄期间定期进行视网膜检影验光。使用1%的环喷托酯来实现睫状肌麻痹。计算每个孩子屈光不正的等效球镜度,并根据父母的屈光状态进行方差分析。从大约20周龄起,发现父母双方均为近视的婴儿与父母双方均非近视的婴儿的屈光不正等效球镜度均值之间存在显著差异。在40周龄时,获得了与常染色体隐性遗传概率模型的良好拟合。

相似文献

1
Autosomal recessive inheritance of myopia in Hong Kong Chinese infants.香港华裔婴儿近视的常染色体隐性遗传
Ophthalmic Physiol Opt. 1991 Jul;11(3):227-31.
2
Effect of parental myopia on the development of myopia in Hong Kong Chinese.父母近视对香港华人近视发展的影响。
Ophthalmic Physiol Opt. 1998 Nov;18(6):477-83.
3
The refractive status of Hong Kong Chinese infants.香港华裔婴儿的屈光状态。
Ophthalmic Physiol Opt. 1991 Oct;11(4):297-303.
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Ocular anisometropia and laterality.眼性屈光参差与眼别
Acta Ophthalmol Scand. 2004 Apr;82(2):175-8. doi: 10.1111/j.1600-0420.2004.00230.x.
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The development of myopia up to the age of twenty and a comparison of refraction in parents and children.20岁前近视的发展以及父母与子女屈光情况的比较。
Arctic Med Res. 1993 Oct;52(4):161-5.
6
[Pedigree study of pathological myopia].[病理性近视的家系研究]
Yi Chuan Xue Bao. 2005 Feb;32(2):130-5.
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Analysis of refractive status of Hong Kong Chinese infants.香港华裔婴儿屈光状态分析。
Ophthalmic Physiol Opt. 1992 Oct;12(4):478-80.
8
Changes in refractive trends and optical components of Hong Kong Chinese aged 19-39 years.19至39岁香港华人的屈光趋势及眼部光学部件的变化
Ophthalmic Physiol Opt. 1994 Oct;14(4):378-82.
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Age of first distance prescription and final myopic refractive error.首次远距离处方年龄与最终近视屈光不正度数。
Ophthalmic Epidemiol. 2009 Mar-Apr;16(2):84-9. doi: 10.1080/09286580802624442.
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Changes in refractive trends and optical components of Hong Kong Chinese aged over 40 years.40岁以上香港华人屈光趋势及眼屈光成分的变化
Ophthalmic Physiol Opt. 1994 Oct;14(4):383-8.

引用本文的文献

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Identification of novel suggestive loci for high-grade myopia in Polish families.波兰家族中高度近视新的潜在基因座的鉴定。
Mol Vis. 2011;17:2028-39. Epub 2011 Jul 22.
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Clinical and linkage study on a consanguineous Chinese family with autosomal recessive high myopia.一个患有常染色体隐性高度近视的中国近亲家庭的临床及连锁研究
Mol Vis. 2009;15:312-8. Epub 2009 Feb 9.
3
Familial aggregation of myopia in the Tehran eye study: estimation of the sibling and parent offspring recurrence risk ratios.德黑兰眼病研究中近视的家族聚集性:兄弟姐妹及亲子复发风险比的估计
Br J Ophthalmol. 2007 Nov;91(11):1440-4. doi: 10.1136/bjo.2007.120162. Epub 2007 May 10.
4
Evidence that a locus for familial high myopia maps to chromosome 18p.有证据表明家族性高度近视的一个基因座定位于18号染色体短臂。
Am J Hum Genet. 1998 Jul;63(1):109-19. doi: 10.1086/301907.