一种简化的p24检测法用于海地1型人类免疫缺陷病毒婴儿感染早期诊断的潜力
Potential of a simplified p24 assay for early diagnosis of infant human immunodeficiency virus type 1 infection in Haiti.
作者信息
George Erik, Beauharnais Carole Anne, Brignoli Emilio, Noel Francine, Bois Gyrlande, De Matteis Rouzier Patricia, Altenor Martine, Lauture Daniel, Hosty Marlène, Mehta Sapna, Wright Peter F, Pape Jean W
机构信息
Department of Medicine, Weill Medical College, Cornell University, New York, NY, USA.
出版信息
J Clin Microbiol. 2007 Oct;45(10):3416-8. doi: 10.1128/JCM.01314-07. Epub 2007 Aug 1.
Abstract
With global efforts to scale up the prevention of mother-to-child transmission services and pediatric antiretroviral therapy, there is an urgent need to introduce a simple, low-cost infant human immunodeficiency virus test in the field. We postulated that the p24 antigen capture enzyme-linked immunosorbent assay could be simplified by eliminating signal amplification without compromising diagnostic accuracy.
摘要
随着全球加大力度扩大预防母婴传播服务和儿科抗逆转录病毒疗法的规模，在该领域迫切需要引入一种简单、低成本的婴儿人类免疫缺陷病毒检测方法。我们推测，通过消除信号放大而不影响诊断准确性，可以简化p24抗原捕获酶联免疫吸附测定法。
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