Akers Katherine G, Hamilton Derek A
Department of Psychology, University of New Mexico, Albuquerque, NM 87131, USA.
Dev Psychobiol. 2007 Sep;49(6):553-64. doi: 10.1002/dev.20227.
Previous studies investigating the development of place and cued learning using the Morris water task are in disagreement regarding the day in development that each type of learning emerges. Here, place and cued navigation in the water task were examined in differently aged groups of young male and female rats (P17, P18, P19, P20, and P24) during a single day of training. When only distal cues were present, P20 and P24 but not younger rats learned the location of the hidden platform. In contrast, when a proximal cue marked the platform location, rats as young as P17 showed evidence of cue-controlled navigation, although only P18 and older rats exhibited cued learning. In line with most previous studies, these results indicate that cued learning emerges earlier in development than place learning and support a dissociation of developmental trajectories for the neural systems underlying the two types of navigation.
以往利用莫里斯水迷宫任务研究位置学习和线索学习发展情况的研究，在每种学习类型出现的发育天数上存在分歧。在此，在一天训练期间，对不同年龄组的年轻雄性和雌性大鼠（P17、P18、P19、P20和P24）进行了水迷宫任务中的位置导航和线索导航测试。当仅存在远端线索时，P20和P24的大鼠学会了隐藏平台的位置，而较年幼的大鼠则没有。相比之下，当有近端线索标记平台位置时，年仅P17的大鼠就表现出线索控制导航的迹象，不过只有P18及更大年龄的大鼠表现出线索学习。与大多数以往研究一致，这些结果表明线索学习在发育过程中比位置学习出现得更早，并支持两种导航类型背后神经系统发育轨迹的分离。
