Magiati Iliana, Charman Tony, Howlin Patricia
Institute of Psychiatry, King's College London, UK.
J Child Psychol Psychiatry. 2007 Aug;48(8):803-12. doi: 10.1111/j.1469-7610.2007.01756.x.
This prospective study compared outcome for pre-school children with autism spectrum disorders (ASD) receiving autism-specific nursery provision or home-based Early Intensive Behavioural Interventions (EIBI) in a community setting.
Forty-four 23- to 53-month-old children with ASD participated (28 in EIBI home-based programmes; 16 in autism-specific nurseries). Cognitive, language, play, adaptive behaviour skills and severity of autism were assessed at intake and 2 years later.
Both groups showed improvements in age equivalent scores but standard scores changed little over time. At follow-up, there were no significant group differences in cognitive ability, language, play or severity of autism. The only difference approaching significance (p = .06), in favour of the EIBI group, was for Vineland Daily Living Skills standard scores. However, there were large individual differences in progress, with intake IQ and language level best predicting overall progress.
Home-based EIBI, as implemented in the community, and autism-specific nursery provision produced comparable outcomes after two years of intervention.
本前瞻性研究比较了社区环境中接受自闭症专项幼儿园服务或家庭式早期密集行为干预（EIBI）的学龄前自闭症谱系障碍（ASD）儿童的治疗效果。
44名年龄在23至53个月的ASD儿童参与研究（28名参与家庭式EIBI项目；16名在自闭症专项幼儿园）。在入组时和两年后对认知、语言、玩耍、适应性行为技能以及自闭症严重程度进行评估。
两组的年龄当量分数均有所提高，但标准分数随时间变化不大。随访时，两组在认知能力、语言、玩耍或自闭症严重程度方面无显著差异。唯一接近显著差异（p = 0.06）且有利于EIBI组的是文兰日常生活技能标准分数。然而，进展存在很大的个体差异，入组时的智商和语言水平最能预测总体进展。
在社区实施的家庭式EIBI和自闭症专项幼儿园服务在两年干预后产生了相当的效果。
