Trachtman H, Gauthier B, Vinograd A, Valderrama E
Department of Pediatrics, Schneider Children's Hospital, New Hyde Park, New York 11042.
Pediatr Nephrol. 1991 Nov;5(6):724-6. doi: 10.1007/BF00857885.
Infection with the human immunodeficiency virus type 1 (HIV-1) can cause a spectrum of renal disease, termed acquired immunodeficiency syndrome (AIDS) nephropathy. The most common clinical manifestations of kidney involvement in HIV-1-infected patients are proteinuria and/or nephrotic syndrome, and the histopathological pattern usually reveals focal segmental glomerulosclerosis. We describe an 8-year-old child with AIDS who presented with recurrent gross hematuria. A kidney biopsy demonstrated IgA nephropathy. This unique case indicates that the range of kidney disease in HIV-infected children may be broader than originally thought, and that these patients warrant a complete evaluation of any renal abnormality.
感染1型人类免疫缺陷病毒（HIV-1）可引发一系列肾脏疾病，称为获得性免疫缺陷综合征（AIDS）肾病。HIV-1感染患者肾脏受累的最常见临床表现是蛋白尿和/或肾病综合征，组织病理学模式通常显示局灶节段性肾小球硬化。我们描述了一名8岁的艾滋病患儿，其表现为反复肉眼血尿。肾脏活检显示为IgA肾病。这一独特病例表明，HIV感染儿童的肾脏疾病范围可能比最初认为的更广，这些患者的任何肾脏异常都需要进行全面评估。
