Resnikoff S, Filliard G, Dell'Aquila B
OCCGE-Institut d'Ophtalmogie Tropicale de l'Afrique (Institute of African Tropical Ophthalmology), Bamako, Mali.
Br J Ophthalmol. 1991 Dec;75(12):734-6. doi: 10.1136/bjo.75.12.734.
During a countrywide survey we assessed the prevalence of climatic droplet keratopathy (CDK) in a randomised sample of 2446 subjects representative of the population of the Republic of Djibouti. The investigation of the relationship between CDK and two diseases considered to be related to exposure to ultra-violet light--namely, exfoliation syndrome and cataract--was planned as a case control study. In the rural area prevalence of CDK was five times higher than in the urban one (2.8% vs 0.5%) and varied according to districts. The highest rates were observed where the inhabitants' activities were related to the sea. The case control study revealed that the opacification of the lens was about three times commoner in patients with CDK than in patients without CDK (p = 0.03) and that the exfoliation syndrome was about six times commoner in patients with CDK than in controls of similar age, sex, climatic conditions, and lens status (p = 0.02). Moreover, we noticed that the sequelae of corneal perforations were about 30 times commoner in patients with CDK than in controls of similar age (p less than 0.00001).
在一项全国性调查中，我们对吉布提共和国具有代表性的2446名随机抽样受试者进行了评估，以确定气候性小滴状角膜病变（CDK）的患病率。作为一项病例对照研究，我们计划调查CDK与另外两种被认为与紫外线暴露有关的疾病，即剥脱综合征和白内障之间的关系。在农村地区，CDK的患病率比城市地区高五倍（2.8%对0.5%），且因地区而异。在居民活动与海洋相关的地区观察到最高发病率。病例对照研究显示，CDK患者晶状体混浊的发生率约为非CDK患者的三倍（p = 0.03），剥脱综合征在CDK患者中的发生率约为年龄、性别、气候条件和晶状体状态相似的对照组的六倍（p = 0.02）。此外，我们注意到，CDK患者角膜穿孔后遗症的发生率约为年龄相似的对照组的30倍（p < 0.00001）。
