Department of Ophthalmology and the Eye Institute, Eye and Ear, Nose, and Throat Hospital, Fudan University, 83 Fenyang Rd., Shanghai, People's Republic of China.
Key NHC Key Laboratory of Myopia (Fudan University), Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, 200031, China.
BMC Ophthalmol. 2021 Aug 30;21(1):316. doi: 10.1186/s12886-021-02065-4.
Investigation of the prevalence of climatic droplet keratopathy (CDK) in Tacheng, Xinjiang, China.
A total of 1030 participants, in their 40s or older, from the Kazakh ethnic group in Tacheng, were randomly sampled by stratification method. Ophthalmic examinations and surveys were carried out on these participants. Factors associated with CDK were analyzed with logistic regression models.
CDK was found in 66 (6.4%; 95% confidence interval [CI]: 4.9-7.9%) Kazakh individuals. After multiple regression model analysis, it demonstrated that age (< 0.001), exposure time (< 0.001), exposure protection (< 0.001), and vegetable intake (< 0.001) were of correlation with CDK, of which age (OR = 1.21[CI]: 1.16-1.27) and long-term outdoor exposure (OR = 2.42[CI]: 1.26-4.67) were the risk factors, and that vegetable intake (OR = 0.29[CI]: 0.14-0.59) and wearing a hat (OR = 0.24[CI]: 0.10-0.56) were protective factors.
This study has revealed the risk and protective factors of CDK, providing a new insight on related research.
调查中国新疆塔城地区气候性滴状角膜病变（CDK）的患病率。
采用分层抽样方法，随机抽取塔城地区哈萨克族 40 岁及以上的 1030 名参与者。对这些参与者进行眼科检查和调查。使用逻辑回归模型分析与 CDK 相关的因素。
在 66 名（6.4%；95%置信区间[CI]：4.9-7.9%）哈萨克族个体中发现了 CDK。经多元回归模型分析，表明年龄（<0.001）、暴露时间（<0.001）、暴露防护（<0.001）和蔬菜摄入（<0.001）与 CDK 相关，其中年龄（OR=1.21[CI]：1.16-1.27）和长期户外暴露（OR=2.42[CI]：1.26-4.67）是危险因素，而蔬菜摄入（OR=0.29[CI]：0.14-0.59）和戴帽子（OR=0.24[CI]：0.10-0.56）是保护因素。
本研究揭示了 CDK 的风险和保护因素，为相关研究提供了新的视角。
