报告分子相互作用实验（MIMIx）所需的最低信息。

The minimum information required for reporting a molecular interaction experiment (MIMIx).

作者信息

Orchard Sandra, Salwinski Lukasz, Kerrien Samuel, Montecchi-Palazzi Luisa, Oesterheld Matthias, Stümpflen Volker, Ceol Arnaud, Chatr-aryamontri Andrew, Armstrong John, Woollard Peter, Salama John J, Moore Susan, Wojcik Jérôme, Bader Gary D, Vidal Marc, Cusick Michael E, Gerstein Mark, Gavin Anne-Claude, Superti-Furga Giulio, Greenblatt Jack, Bader Joel, Uetz Peter, Tyers Mike, Legrain Pierre, Fields Stan, Mulder Nicola, Gilson Michael, Niepmann Michael, Burgoon Lyle, De Las Rivas Javier, Prieto Carlos, Perreau Victoria M, Hogue Chris, Mewes Hans-Werner, Apweiler Rolf, Xenarios Ioannis, Eisenberg David, Cesareni Gianni, Hermjakob Henning

机构信息

European Molecular Biology Laboratory (EMBL) - European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, UK.

出版信息

Nat Biotechnol. 2007 Aug;25(8):894-8. doi: 10.1038/nbt1324.

DOI:10.1038/nbt1324

PMID:17687370

Abstract

A wealth of molecular interaction data is available in the literature, ranging from large-scale datasets to a single interaction confirmed by several different techniques. These data are all too often reported either as free text or in tables of variable format, and are often missing key pieces of information essential for a full understanding of the experiment. Here we propose MIMIx, the minimum information required for reporting a molecular interaction experiment. Adherence to these reporting guidelines will result in publications of increased clarity and usefulness to the scientific community and will support the rapid, systematic capture of molecular interaction data in public databases, thereby improving access to valuable interaction data.

摘要

文献中可获取大量分子相互作用数据，从大规模数据集到经多种不同技术确认的单个相互作用。这些数据常常要么以自由文本形式报告，要么以格式各异的表格形式呈现，而且往往缺少全面理解实验所需的关键信息。在此，我们提出了MIMIx，即报告分子相互作用实验所需的最小信息。遵循这些报告指南将使出版物对科学界而言更加清晰且有用，并将支持在公共数据库中快速、系统地获取分子相互作用数据，从而改善对有价值的相互作用数据的获取。