Lacikova Lubica, Muselik Jan, Masterova Irena, Grancai Daniel
Department of Pharmacognosy and Botany, Faculty of Pharmacy, Comenius University, Odbojárov 10, Bratislava, Slovakia.
Molecules. 2007 Jan 29;12(1):98-102. doi: 10.3390/12010098.
Staphylea L. is a deciduous ornamental shrub that possesses significant cytotoxic and antibacterial activity, although the chemical composition of its extracts and the identity of the structures responsible for these biological activities are not yet known. In this study we have determined the total phenolic content in chloroform and ethyl acetate extracts of four Staphylea species: Staphylea colchica Stev., S. elegans Zab., S. holocarpa Hemsl. and S. pinnata L.. The antioxidant potential (DPPH radical and peroxynitrite scavenging activity) of these extracts was also determined and a correlation between the phenolic content and antioxidant activities of the ethyl acetate extracts has been found. Ethyl acetate extracts were more active and one of them, obtained from S. colchica Stev., possessed the highest activity.
省沽油属植物是一种落叶观赏灌木,具有显著的细胞毒性和抗菌活性,尽管其提取物的化学成分以及负责这些生物活性的结构尚不明确。在本研究中,我们测定了四种省沽油属植物:秋花省沽油(Staphylea colchica Stev.)、秀丽省沽油(S. elegans Zab.)、全果省沽油(S. holocarpa Hemsl.)和羽叶省沽油(S. pinnata L.)的氯仿提取物和乙酸乙酯提取物中的总酚含量。还测定了这些提取物的抗氧化潜力(DPPH自由基清除活性和过氧亚硝酸根清除活性),并发现乙酸乙酯提取物的酚含量与抗氧化活性之间存在相关性。乙酸乙酯提取物活性更高,其中一种来自秋花省沽油(Staphylea colchica Stev.)的提取物活性最高。