Vaughan J A, Noden B H, Beier J C
Department of Immunology and Infectious Diseases, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland 21205.
J Med Entomol. 1991 Nov;28(6):780-6. doi: 10.1093/jmedent/28.6.780.
Erythrocyte densities in the blood meals of six Anopheles mosquito species were compared with those of human host erythrocyte densities. During engorgement, An. gambiae Giles and An. stephensi Liston concentrated erythrocytes by factors of 1.8 and 1.7, respectively; An. freeborni Aitken did not concentrate; and An. arabiensis Patton and An. dirus Peyton & Harrison demonstrated an intermediate level of erythrocyte concentration (1.4 and 1.2, respectively). An. albimanus concentrated host hemoglobin, but hemolysis during engorgement decreased bloodmeal erythrocyte density below that of host blood. The degree to which anopheline species concentrated erythrocytes was related to the frequency and time spent undergoing prediuresis (anal excretion of fluid during feeding), suggesting that prediuresis is responsible for erythrocyte concentration and that the fluid produced represents efflux from the filtration of ingested blood. Differences observed in erythrocyte concentration by different anopheline species are consistent with species-specific patterns of host selection.
将六种按蚊血餐中的红细胞密度与人类宿主的红细胞密度进行了比较。在吸血过程中，冈比亚按蚊（An. gambiae Giles）和斯氏按蚊（An. stephensi Liston）分别将红细胞浓缩了1.8倍和1.7倍；弗里伯恩按蚊（An. freeborni Aitken）没有浓缩；阿拉伯按蚊（An. arabiensis Patton）和大劣按蚊（An. dirus Peyton & Harrison）表现出中等程度的红细胞浓缩水平（分别为1.4倍和1.2倍）。白跗按蚊（An. albimanus）浓缩了宿主血红蛋白，但吸血过程中的溶血作用使血餐红细胞密度低于宿主血液。按蚊种类对红细胞的浓缩程度与进行排尿前期（进食期间从肛门排出液体）的频率和时间有关，这表明排尿前期是红细胞浓缩的原因，并且产生的液体代表了摄入血液过滤后的流出物。不同按蚊种类在红细胞浓缩方面观察到的差异与宿主选择的物种特异性模式一致。
