Son Sang Jun, Bai Xia, Lee Sang Bok
Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
Drug Discov Today. 2007 Aug;12(15-16):657-63. doi: 10.1016/j.drudis.2007.06.012. Epub 2007 Aug 1.
Inorganic nanoparticles, such as carbon nanotubes, quantum dots and gold nanoshells, have been adopted for biomedical use, due to their unique optical and physical properties. Compared to conventional materials, inorganic nanomaterials have several advantages such as simple preparative processes and precise control over their shape, composition and size. In addition, inorganic porous nanomaterials are fundamentally advantageous for developing multifunctional nanomaterials, due to their distinctive inner and outer surfaces. In this review, we describe recent developments of hollow and porous inorganic nanomaterials in nanomedicine, especially for imaging/diagnosis and photothermal therapy.
无机纳米粒子，如碳纳米管、量子点和金纳米壳，由于其独特的光学和物理性质，已被用于生物医学领域。与传统材料相比，无机纳米材料具有几个优点，如制备工艺简单，且能精确控制其形状、组成和尺寸。此外，无机多孔纳米材料因其独特的内外表面，在开发多功能纳米材料方面具有根本优势。在这篇综述中，我们描述了中空和多孔无机纳米材料在纳米医学中的最新进展，特别是在成像/诊断和光热治疗方面。
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