Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, Zabolotny Str,, 154, Kyiv 03680, Ukraine.
EPMA J. 2013 Jun 24;4(1):18. doi: 10.1186/1878-5085-4-18.
The article overviews the potential biomedical applications of nanoscale gold particles for predictive, preventive and personalised nanomedicine in cardiology. The review demonstrates the wide opportunities for gold nanoparticles due to their unique biological properties. The use of gold nanoparticles in cardiology is promising to develop fundamentally new methods of diagnosis and treatment. The nanotheranostics in cardiovascular diseases allows the non-invasive imaging associated with simultaneous therapeutic intervention and predicting treatment outcomes. Imaging may reflect the effectiveness of treatment and has become a fundamental optimisation setting for therapeutic protocol. Combining the application of biomolecular and cellular therapies with nanotechnologies foresees the development of complex integrated nanodevices. Nanocardiology may challenge existing healthcare system and economic benefits as cardiovascular diseases are the leading cause of morbidity and mortality at present.
本文综述了纳米金颗粒在心脏病学中用于预测性、预防性和个体化纳米医学的潜在生物医学应用。该综述展示了由于其独特的生物学特性，金纳米粒子具有广泛的应用机会。在心脏病学中使用金纳米粒子有希望开发出全新的诊断和治疗方法。纳米治疗学在心血管疾病中的应用允许进行与同时治疗干预和预测治疗结果相关的非侵入性成像。成像可以反映治疗的效果，并已成为治疗方案的基本优化设置。将生物分子和细胞疗法与纳米技术的应用相结合，可以预见复杂的集成纳米器件的发展。纳米心脏病学可能会对现有的医疗保健系统和经济效益提出挑战，因为心血管疾病是目前发病率和死亡率的主要原因。
