Behrens Ron H, Carroll Bernadette, Beran Jiri, Bouchaud Olivier, Hellgren Urban, Hatz Christoph, Jelinek Tomas, Legros Fabrice, Mühlberger Nikolai, Myrvang Bjørn, Siikamäki Heli, Visser Leo
Travel Clinic, Hospital for Tropical Diseases, Mortimer Market, London, WC1E 6JB, UK.
Malar J. 2007 Aug 23;6:114. doi: 10.1186/1475-2875-6-114.
A comparison was made between local malaria transmission and malaria imported by travellers to identify the utility of national and regional annual parasite index (API) in predicting malaria risk and its value in generating recommendations on malaria prophylaxis for travellers. Regional malaria transmission data was correlated with malaria acquired in Latin America and imported into the USA and nine European countries. Between 2000 and 2004, most countries reported declining malaria transmission. Highest API's in 2003/4 were in Surinam (287.4) Guyana (209.2) and French Guiana (147.4). The major source of travel associated malaria was Honduras, French Guiana, Guatemala, Mexico and Ecuador. During 2004 there were 6.3 million visits from the ten study countries and in 2005, 209 cases of malaria of which 22 (11%) were Plasmodium falciparum. The risk of adverse events are high and the benefit of avoided benign vivax malaria is very low under current policy, which may be causing more harm than benefit.
对本地疟疾传播情况与旅行者输入的疟疾进行了比较，以确定国家和区域年度寄生虫指数（API）在预测疟疾风险方面的效用及其在为旅行者制定疟疾预防建议方面的价值。区域疟疾传播数据与在拉丁美洲感染并输入美国和九个欧洲国家的疟疾情况相关。2000年至2004年期间，大多数国家报告疟疾传播呈下降趋势。2003/2004年API最高的是苏里南（287.4）、圭亚那（209.2）和法属圭亚那（147.4）。与旅行相关的疟疾的主要来源地是洪都拉斯、法属圭亚那、危地马拉、墨西哥和厄瓜多尔。2004年，来自十个研究国家的访问量为630万次，2005年有209例疟疾病例，其中22例（11%）为恶性疟原虫。根据现行政策，不良事件风险很高，避免良性间日疟的益处非常低，这可能弊大于利。
