Abdulmedzhidova A G, Kurilo L F, Shileĭko L V, Makarova N P, Klimova R R, Kushch A A
Urologiia. 2007 May-Jun(3):56-9.
Incidence of Herpes simplex virus (HSV) was studied in ejaculates of 100 men. The examinees had neither history nor clinical symptoms of HSV genital infection. HSV was detected by a rapid cultural method in the ejaculate of 20 out of 100 examinees (20%). Of 67 males with infertility HSV was detected in 25%, in 19 males examined prophylactically and 14 patients with varicocele (a comparison group) it was found in 10.5 and 7% cases, respectively. Oligozoospermia was two times more frequent in HSV-containing ejaculates than in HSV-negative one. Mean values of the majority of sperm parameters in HSV-positive and HSV-negative groups did not differ statistically. However, it was revealed that such damage of the spermatozoa structure as microhead (consequence of the defective acrosome or reduced genome) and cytoplasm drops on the neck (a sign of immature forms) occurred more often in HSV-infected patients than in persons with HSV-negative ejaculate. Thus, asymptomatic HSV infection has a negative effect on male fertility.
对100名男性的精液进行了单纯疱疹病毒(HSV)感染率的研究。受检者既无HSV生殖器感染病史,也无相关临床症状。采用快速培养法在100名受检者中的20人(20%)精液中检测到HSV。在67名不育男性中,HSV检测阳性率为25%;在19名接受预防性检查的男性以及14名精索静脉曲张患者(对照组)中,HSV检测阳性率分别为10.5%和7%。含HSV的精液中少精子症的发生率是HSV阴性精液的两倍。HSV阳性组和HSV阴性组大多数精子参数的平均值在统计学上无差异。然而,研究发现,与HSV阴性精液者相比,HSV感染患者中精子头部微小(顶体缺陷或基因组减少的结果)和颈部出现细胞质滴(不成熟形态的标志)等精子结构损伤更为常见。因此,无症状HSV感染对男性生育能力有负面影响。