Fang J C, Bodeus M, Burtonboy G
Department of Cell Biology, Beijing Institute for Cancer Research, China.
Chin J Biotechnol. 1991;7(1):73-81.
The rat-rat hybridoma technique has some definite advantages in the three systems (mouse, rat or human system) currently utilized for monoclonal antibody production. The study on rat-rat hybridoma technique and its application to the productions of monoclonal antibodies against human immunodeficiency virus (HIV) and hepatitis B virus surface antigen (HBsAg) are described as examples in this paper.
大鼠-大鼠杂交瘤技术在目前用于单克隆抗体制备的三种系统（小鼠、大鼠或人类系统）中具有一些明确的优势。本文以大鼠-大鼠杂交瘤技术及其在抗人类免疫缺陷病毒（HIV）和乙型肝炎病毒表面抗原（HBsAg）单克隆抗体制备中的应用研究为例进行阐述。
