Seagroatt V, Tan H S, Goldacre M, Bulstrode C, Nugent I, Gill L
Department of Public Health and Primary Care, University of Oxford.
BMJ. 1991 Dec 7;303(6815):1431-5. doi: 10.1136/bmj.303.6815.1431.
To report the incidence of elective total hip replacement and postoperative mortality, emergency readmission rates, and the demographic factors associated with these rates in a large defined population.
Analysis of linked, routine abstracts of hospital inpatient records and death certificates.
10 hospitals in six districts in Oxford Regional Health Authority covered by the Oxford record linkage study.
Records for 11,607 total hip replacements performed electively in 1976-85.
Incidence of operation, postoperative mortality, relative mortality ratios, and incidence of emergency readmission.
NHS operation rates increased over time from 43 to 58 operations/100,000 population. Variation in operation rates between districts reduced over time. Operation rates were on average 25% higher in women than men. There were 93 deaths (11/1000 operations) within 90 days of the operation and 208 emergency readmissions (28/1000 operations) within 28 days of discharge. Postoperative mortality and emergency readmission rates increased with age. No significant trend with time was found. Mortality in the 90 days after the operation was 2.5-fold higher (1.9 to 3.0) than in the rest of the first postoperative year. This represented an estimated excess of 6.5 (4.2 to 8.8) early postoperative deaths/1000 operations. Most deaths were ascribed to cardiovascular events. Thromboembolic disease was the commonest reason for emergency readmission.
The pronounced increase in operations in districts with initially low rates suggests a trend towards greater equity in the local provision of NHS hip arthroplasty. The early postoperative clusters of deaths attributed to cardiovascular disease and of readmissions for thromboembolic disease suggest that there is scope for investigating ways of reducing the incidence of major adverse postoperative events.
报告在一个明确界定的大型人群中,择期全髋关节置换术的发生率、术后死亡率、急诊再入院率以及与这些比率相关的人口统计学因素。
对医院住院记录和死亡证明的关联常规摘要进行分析。
牛津地区卫生局六个区的10家医院,涵盖牛津记录链接研究。
1976 - 1985年期间择期进行的11,607例全髋关节置换术的记录。
手术发生率、术后死亡率、相对死亡率以及急诊再入院率。
国民健康服务体系(NHS)的手术率随时间从每10万人43例增加到58例。各地区手术率的差异随时间减小。女性的手术率平均比男性高25%。术后90天内有93例死亡(每1000例手术中有11例),出院后28天内有208例急诊再入院(每1000例手术中有28例)。术后死亡率和急诊再入院率随年龄增加。未发现随时间的显著趋势。术后90天内的死亡率比术后第一年其余时间高2.5倍(1.9至3.0)。这相当于每1000例手术估计有6.5例(4.2至8.8例)术后早期死亡。大多数死亡归因于心血管事件。血栓栓塞性疾病是急诊再入院最常见的原因。
最初手术率较低地区的手术率显著增加,表明在当地提供国民健康服务体系髋关节置换术方面有朝着更大公平性发展的趋势。术后早期因心血管疾病导致的死亡聚集以及因血栓栓塞性疾病再入院的情况表明,有必要研究降低术后重大不良事件发生率的方法。