Seagroatt V, Goldacre M
Department of Public Health and Primary Care, University of Oxford.
BMJ. 1994 Aug 6;309(6951):361-5; discussion 365-6. doi: 10.1136/bmj.309.6951.361.
To quantify the short term risk of postoperative mortality in ways which take account of deaths after discharge and the background risks of death in patients who come to operation.
Analysis of linked abstracts of hospital admission records and death certificates for common operations.
Six health districts in the Oxford region.
Records of 223,529 operations performed in 1980-6.
In hospital fatality rates, case fatality rates, and standardised mortality ratios at selected time periods during the year after operation and the ratio of early (< 30 days) to late (90-364 days after operation) fatality rates.
Fatality rates throughout the year after operations performed after emergency admissions were generally higher than those for similar operations performed after elective admissions and higher than expected from population rates. Examples were prostatectomy, hip arthroplasty, inguinal herniorrhaphy, and cholecystectomy. Common elective operations such as inguinal herniorrhaphy and cataract operations showed no early peak in mortality, but others did. These included transurethral prostatectomy (ratio of early to late mortality 2.0; 95% confidence interval 1.3 to 2.6), hysterectomy (3.2; 1.5 to 6.6), hip arthroplasty (3.8; 2.5 to 5.4), and cholecystectomy (6.9; 4.3 to 11.1).
Temporal profiles of death rates in the year after operation show which operations have early peaks in mortality and which do not. Emergency and elective operations have very different profiles and should be analysed separately. For elective operations for conditions which pose no immediate threat to life the ratio of early to later fatality rates provides a measure of increase in mortality after operation while allowing for the background risk of death in the patient groups.
采用考虑出院后死亡情况及手术患者死亡背景风险的方法,对术后短期死亡风险进行量化。
对常见手术的医院入院记录和死亡证明的关联摘要进行分析。
牛津地区的六个卫生区。
1980 - 1986年期间进行的223529例手术记录。
术后一年内特定时间段的住院死亡率、病例死亡率和标准化死亡比,以及早期(<30天)与晚期(术后90 - 364天)死亡率之比。
急诊入院后进行的手术全年死亡率普遍高于择期入院后进行的类似手术,且高于人群预期死亡率。例如前列腺切除术、髋关节置换术、腹股沟疝修补术和胆囊切除术。腹股沟疝修补术和白内障手术等常见择期手术未显示出早期死亡高峰,但其他手术有。这些手术包括经尿道前列腺切除术(早期与晚期死亡率之比为2.0;95%置信区间为1.3至2.6)、子宫切除术(3.2;1.5至6.6)、髋关节置换术(3.8;2.5至5.4)和胆囊切除术(6.9;4.3至11.1)。
术后一年的死亡率时间分布显示了哪些手术有早期死亡高峰,哪些没有。急诊手术和择期手术的分布差异很大,应分别进行分析。对于对生命无直接威胁的疾病进行的择期手术,早期与晚期死亡率之比可衡量术后死亡率的增加,同时考虑患者群体的死亡背景风险。