Howell G A, Perez-Clausell J, Frederickson C J
Laboratory for Neurobiology, University of Texas, Dallas, Richardson 75083.
Brain Res. 1991 Oct 25;562(2):181-9. doi: 10.1016/0006-8993(91)90620-b.
A retrograde tracing method that selectively labels the perikarya of zinc-containing neurons was used to identify the neurons that supply zinc-containing fibers to the bed nucleus of the stria terminalis in the rat. In agreement with prior lesion studies, retrograde tracing indicates that neurons in amygdalar and periamygdalar regions are the major sources of the zinc-containing innervation of the bed nucleus complex. Zinc-containing neurons in the presubiculum and prosubiculum were also retrogradely labeled from the BNST, whereas cells of the subiculum proper did not label. Light and occasional retrograde labeling of some CA1 and CA2 neurons and limbic cortical neurons was also observed, but the possibility of transport from regions bordering BNST injections (septum, caudate-putamen) could not be excluded in the latter cases.
采用一种能选择性标记含锌神经元胞体的逆行追踪方法，来鉴定向大鼠终纹床核提供含锌纤维的神经元。与先前的损伤研究一致，逆行追踪表明杏仁核和杏仁周区域的神经元是终纹床核复合体含锌神经支配的主要来源。前下托和下托前区的含锌神经元也可从终纹床核被逆行标记，而真正的下托细胞则未被标记。还观察到一些CA1和CA2神经元以及边缘皮质神经元有轻度且偶尔的逆行标记，但在后一种情况下，不能排除来自终纹床核注射部位周边区域（隔区、尾状核-壳核）的运输可能性。
