Holt Dennis M, Watts J Dustin, Beeson Thomas J, Kirkpatrick Timothy C, Rutledge Richard E
Department of Endodontics, Wilford Hall Medical Center, Lackland AFB, Texas 78236-5346, USA.
J Endod. 2007 Jul;33(7):844-7. doi: 10.1016/j.joen.2007.04.006. Epub 2007 May 18.
The purpose of this in vitro study was 2-fold: First, to compare the antimicrobial effect of gray and tooth-colored mineral trioxide aggregate (MTA) when mixed with sterile water or 2% chlorhexidine. Second, to compare the compressive strengths of the MTA/chlorhexidine versus MTA/sterile water samples. The antimicrobial effect test was accomplished by placing freshly mixed MTA samples on agar plates inoculated with Enterococcus faecalis and comparing the zones of inhibition at 24 hours. In the compressive strength test, MTA pellets were allowed to set for 72 hours and then compressed to fracture by using an Instron testing machine. Values were recorded and compared. In the antimicrobial effect experiment, the zones of inhibition were significantly larger for samples mixed with 2% chlorhexidine. In the compressive strength study, statistical evaluation showed no significance due to variability. However, data revealed that MTA mixed with sterile water always had higher compressive strengths than MTA mixed with chlorhexidine.
第一，比较灰色和牙色的三氧化矿物凝聚体（MTA）与无菌水或2%氯己定混合时的抗菌效果。第二，比较MTA/氯己定与MTA/无菌水样本的抗压强度。抗菌效果测试是通过将新混合的MTA样本放置在接种粪肠球菌的琼脂平板上，并比较24小时后的抑菌圈来完成的。在抗压强度测试中，让MTA小球凝固72小时，然后使用英斯特朗测试机压缩至破裂。记录并比较数值。在抗菌效果实验中，与2%氯己定混合的样本的抑菌圈明显更大。在抗压强度研究中，由于变异性，统计评估显示无显著性差异。然而，数据显示，与氯己定混合的MTA相比，与无菌水混合的MTA始终具有更高的抗压强度。
