Salmon E, Maquet P, Sadzot B, Degueldre C, Lemaire C, Franck G
Department of Neurology, University of Liège, Belgium.
Acta Neurol Belg. 1991;91(5):288-95.
Frontal metabolism measured with positron emission tomography is shown to be decreased relatively to that in other cortical or sub-cortical areas, in a population of healthy elderly compared to young volunteers. Cortical atrophy or neuronal depopulation are unlikely to entirely explain this physiological phenomenon, and sub-cortico-cortical deactivation should play a role, analogous to that proposed in subcortical diseases.
与年轻志愿者相比，在健康老年人群体中，正电子发射断层扫描测量的额叶代谢相对于其他皮质或皮质下区域的代谢有所降低。皮质萎缩或神经元减少不太可能完全解释这一生理现象，皮质下-皮质失活应该起到了一定作用，类似于在皮质下疾病中所提出的作用。
