Scully Crispian, Carrozzo Marco
University College London, Eastman Dental Institute, UK.
Br J Oral Maxillofac Surg. 2008 Jan;46(1):15-21. doi: 10.1016/j.bjoms.2007.07.199. Epub 2007 Sep 5.
Lichen planus (LP) is a common disorder in which auto-cytotoxic T lymphocytes trigger apoptosis of epithelial cells leading to chronic inflammation. Oral LP (OLP) can be a source of severe morbidity and has a small potential to be malignant. The diagnosis of OLP can be made from the clinical features if they are sufficiently characteristic, particularly if typical skin or other lesions are present, but biopsy is recommended to confirm the diagnosis and to exclude dysplasia and malignancy. OLP is treated with anti-inflammatory agents, mainly the topical corticosteroids, but newer agents and techniques are becoming available.
扁平苔藓（LP）是一种常见疾病，其中自身细胞毒性T淋巴细胞触发上皮细胞凋亡，导致慢性炎症。口腔扁平苔藓（OLP）可能是严重发病的根源，并有较小的恶变可能性。如果OLP的临床特征足够典型，特别是存在典型的皮肤或其他病变时，可根据临床特征做出诊断，但建议进行活检以确诊并排除发育异常和恶性肿瘤。OLP主要用抗炎药治疗，主要是局部用皮质类固醇，但也有新的药物和技术可供使用。
