Leung Serena B, Egawa Hiroshi, Stepniewski Adam, Beykirch Sarah, Engh C Anderson, Engh Charles A
Anderson Orthopaedic Research Institute, Alexandria, Virginia 22307, USA.
J Arthroplasty. 2007 Sep;22(6 Suppl 2):134-9. doi: 10.1016/j.arth.2007.04.006. Epub 2007 Jul 27.
Highly cross-linked polyethylene has shown decreased wear rates as compared to conventional polyethylene. However, the impact of this decrease on the occurrence of osteolysis remains uncertain. Forty hips implanted with noncross-linked Enduron and 36 implanted with 5-Mrad cross-linked Marathon polyethylene had a computed tomography at a minimum of 5 years after arthroplasty. Polyethylene wear, osteolysis incidence, location, and volume were compared. The incidence of osteolysis was statistically greater for patients with noncross-linked Enduron (11/40, 28%) compared to patients with the moderately cross-linked Marathon (3/36, 8%; P = .04). The average lesion volume for hips with Enduron liners (7.5 +/- 6.7 cm(3)) was significantly greater than the average lesion volume for hips implanted with Marathon liners (1.2 +/- 0.1 cm(3), P = .01). Marathon cross-linked polyethylene has shown to have a decreased incidence and volume of pelvic osteolysis. Longer follow-up is necessary to determine if Marathon cross-linked polyethylene will continue to demonstrate the encouraging improved wear and osteolysis characteristics.
与传统聚乙烯相比,高度交联聚乙烯的磨损率有所降低。然而,这种降低对骨溶解发生的影响仍不确定。对40例植入非交联Enduron的髋关节和36例植入5兆拉德交联Marathon聚乙烯的髋关节在置换术后至少5年进行了计算机断层扫描。比较了聚乙烯磨损、骨溶解发生率、位置和体积。与中度交联的Marathon聚乙烯患者(3/36,8%;P = 0.04)相比,非交联Enduron患者(11/40,28%)的骨溶解发生率在统计学上更高。使用Enduron内衬的髋关节的平均病变体积(7.5±6.7立方厘米)显著大于植入Marathon内衬的髋关节的平均病变体积(1.2±0.1立方厘米,P = 0.01)。Marathon交联聚乙烯已显示出骨盆骨溶解的发生率和体积有所降低。需要更长时间的随访来确定Marathon交联聚乙烯是否会继续表现出令人鼓舞的改善的磨损和骨溶解特性。