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维生素与睡眠:一项探索性研究。

Vitamins and sleep: an exploratory study.

作者信息

Lichstein Kenneth L, Payne Kristen L, Soeffing James P, Heith Durrence H, Taylor Daniel J, Riedel Brant W, Bush Andrew J

机构信息

The University of Alabama, Department of Psychology, Sleep Research Project, Box 870348, Tuscaloosa, AL 35487-0348, USA.

出版信息

Sleep Med. 2007 Dec;9(1):27-32. doi: 10.1016/j.sleep.2006.12.009. Epub 2007 Sep 6.

DOI:10.1016/j.sleep.2006.12.009
PMID:17825610
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2174691/
Abstract

STUDY OBJECTIVE

We analyzed archival data from an epidemiology study to test the association between vitamin use and sleep.

DESIGN

Random digit dialing was used to recruit 772 people ranging in age from 20 to 98 for a study of people's sleep experience. These individuals completed a set of questionnaires about their sleep, health, and daytime functioning. Five hundred and nineteen of these participants had available vitamin use data.

SETTING

Home.

PARTICIPANTS

Five hundred and nineteen people participated. Recruitment applied minimal screening criteria and no attempt was made to favor people with or without sleep disturbance.

INTERVENTIONS

This survey included no intervention. Participants completed 2 weeks of sleep diaries and a set of questionnaires. Of particular salience to the present study, participants reported their vitamin use in listing all medications and nutritional supplements being used currently.

MEASUREMENTS AND RESULTS

For those individuals taking a multivitamin or multiple single vitamins, sleep diaries revealed poorer sleep compared to non-vitamin users in the number and duration of awakenings during the night. After controlling for age, ethnicity, and sex the difference in number of awakenings was still marginally significant. The rate of insomnia, conservatively defined, and consumption of sleep medication were also marginally significantly higher among individuals taking multi-/multiple vitamins compared to those not taking vitamins.

CONCLUSIONS

Disturbed sleep maintenance was associated with multi-/multiple vitamin use. Five equally plausible explanations were advanced to explain this association including vitamins cause poor sleep, poor sleepers seek vitamins, and unidentified factors promote both poor sleep and vitamin use. These data are considered preliminary. Methodological characteristics of future studies were described that hold the promise of more clearly illuminating the association between vitamins and sleep.

摘要

研究目的

我们分析了一项流行病学研究的存档数据,以检验维生素使用与睡眠之间的关联。

设计

采用随机数字拨号的方式招募了772名年龄在20岁至98岁之间的人,以研究人们的睡眠体验。这些个体完成了一组关于他们的睡眠、健康和日间功能的问卷。其中519名参与者有可用的维生素使用数据。

地点

家中。

参与者

519人参与。招募采用了最低限度的筛选标准,没有试图偏袒有或没有睡眠障碍的人。

干预措施

这项调查没有干预措施。参与者完成了2周的睡眠日记和一组问卷。对本研究特别重要的是,参与者在列出目前正在使用的所有药物和营养补充剂时报告了他们的维生素使用情况。

测量与结果

对于那些服用多种维生素或多种单一维生素的个体,睡眠日记显示,与不服用维生素的人相比,他们夜间醒来的次数和持续时间的睡眠质量较差。在控制了年龄、种族和性别后,醒来次数的差异仍然具有微弱的显著性。与不服用维生素的人相比,服用多种/多种维生素的个体中,保守定义的失眠率和睡眠药物的消费量也略高。

结论

睡眠维持障碍与多种/多种维生素的使用有关。提出了五种同样合理的解释来解释这种关联,包括维生素导致睡眠不佳、睡眠不好的人寻求维生素,以及未确定的因素促进睡眠不佳和维生素的使用。这些数据被认为是初步的。描述了未来研究的方法学特征,有望更清楚地阐明维生素与睡眠之间的关联。

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