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基础与临床纳米医学的最新进展。

Recent advances in basic and clinical nanomedicine.

作者信息

Morrow K John, Bawa Raj, Wei Chiming

机构信息

Newport Biotechnology Consultants, 625 Washington Avenue, Newport, KY 41071, USA.

出版信息

Med Clin North Am. 2007 Sep;91(5):805-43. doi: 10.1016/j.mcna.2007.05.009.

Abstract

Nanomedicine is a global business enterprise. Industry and governments clearly are beginning to envision nanomedicine's enormous potential. A clear definition of nanotechnology is an issue that requires urgent attention. This problem exists because nanotechnology represents a cluster of technologies, each of which may have different characteristics and applications. Although numerous novel nanomedicine-related applications are under development or nearing commercialization, the process of converting basic research in nanomedicine into commercially viable products will be long and difficult. Although realization of the full potential of nanomedicine may be years or decades away, recent advances in nanotechnology-related drug delivery, diagnosis, and drug development are beginning to change the landscape of medicine. Site-specific targeted drug delivery and personalized medicine are just a few concepts that are on the horizon.

摘要

纳米医学是一个全球性的商业企业。产业界和政府显然已开始设想纳米医学的巨大潜力。纳米技术的明确定义是一个需要迫切关注的问题。之所以存在这个问题,是因为纳米技术代表了一系列技术,其中每一项技术可能都有不同的特性和应用。尽管众多与纳米医学相关的新颖应用正在研发中或已接近商业化,但将纳米医学的基础研究转化为具有商业可行性的产品的过程将漫长而艰难。尽管纳米医学充分发挥其潜力可能还需数年或数十年时间,但纳米技术在药物递送、诊断和药物研发方面的最新进展正开始改变医学的面貌。位点特异性靶向给药和个性化医疗只是即将出现的一些概念。

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