Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy ; Leibniz Institute for Solid State and Materials Research Dresden, Postfatch 270116, 01171 Dresden, Germany.
Leibniz Institute for Solid State and Materials Research Dresden, Postfatch 270116, 01171 Dresden, Germany.
Biomed Res Int. 2014;2014:825017. doi: 10.1155/2014/825017. Epub 2014 Jan 21.
The use of biologics, polymers, silicon materials, carbon materials, and metals has been proposed for the preparation of innovative drug delivery devices. One of the most promising materials in this field are the carbon-nanotubes composites and hybrid materials coupling the advantages of polymers (biocompatibility and biodegradability) with those of carbon nanotubes (cellular uptake, stability, electromagnatic, and magnetic behavior). The applicability of polymer-carbon nanotubes composites in drug delivery, with particular attention to the controlled release by composites hydrogel, is being extensively investigated in the present review.
生物制剂、聚合物、硅材料、碳材料和金属已被提议用于制备创新型药物输送装置。在这个领域中最有前途的材料之一是碳纳米管复合材料和混合材料,它们结合了聚合物的优点(生物相容性和可生物降解性)和碳纳米管的优点(细胞摄取、稳定性、电磁和磁性行为)。本综述广泛研究了聚合物-碳纳米管复合材料在药物输送中的应用,特别关注复合材料水凝胶的控制释放。