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心血管疾病中的纳米成像:当前技术水平

Nanoimaging in cardiovascular diseases: Current state of the art.

作者信息

Deb Suryyani, Ghosh Kanjaksha, Shetty Shrimati Dharmapal

机构信息

Department of Hemostasis & Thrombosis, National Institute of Immunohaematology (ICMR), Mumbai, India.

出版信息

Indian J Med Res. 2015 Mar;141(3):285-98. doi: 10.4103/0971-5916.156557.

DOI:10.4103/0971-5916.156557
PMID:25963489
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4442326/
Abstract

Nanotechnology has been integrated into healthcare system in terms of diagnosis as well as therapy. The massive impact of imaging nanotechnology has a deeper intervention in cardiology i.e. as contrast agents , to target vulnerable plaques with site specificity and in a theranostic approach to treat these plaques, stem cell delivery in necrotic myocardium, etc. Thus cardiovascular nanoimaging is not limited to simple diagnosis but also can help real time tracking during therapy as well as surgery. The present review provides a comprehensive description of the molecular imaging techniques for cardiovascular diseases with the help of nanotechnology and the potential clinical implications of nanotechnology for future applications.

摘要

纳米技术已在诊断和治疗方面融入医疗保健系统。成像纳米技术的巨大影响在心脏病学领域有更深入的应用,即作为造影剂,以位点特异性靶向易损斑块,并采用治疗诊断方法治疗这些斑块、在坏死心肌中递送干细胞等。因此,心血管纳米成像不仅限于简单诊断,还可在治疗及手术过程中实现实时跟踪。本综述借助纳米技术全面描述了心血管疾病的分子成像技术以及纳米技术在未来应用中的潜在临床意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f747/4442326/db8538b20cc2/IJMR-141-285-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f747/4442326/87c7f0a47744/IJMR-141-285-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f747/4442326/db8538b20cc2/IJMR-141-285-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f747/4442326/87c7f0a47744/IJMR-141-285-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f747/4442326/db8538b20cc2/IJMR-141-285-g006.jpg

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本文引用的文献

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Nanoparticle contrast agents for computed tomography: a focus on micelles.用于计算机断层扫描的纳米颗粒造影剂:聚焦于胶束
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Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases.纳米颗粒介导的药物递送用于治疗心血管疾病。
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